Colistimethate Sodium for Injection I.P.
The following criteria has been proposed for initiating Colistin
For I.V Use Only
- Pan-resistant organism as per culture report with evidence of invasive disease
– fever/ leucocytosis/elevated procalcitonin (PCT) or culture from a sterile site.
- Clinical failure of all other classes of antibiotics over 72 hours
In case of Pan drug resistant Pseudomonas /Acinetobacter spp. combination
therapy using colistin along with beta-lactams (using PK/PD principles) should be discussed